急诊应用胺碘酮治疗冠心病室性心律失常的临床探讨(1)
【摘要】 目的：分析急诊应用胺碘酮治疗冠心病室性心律失常的临床效果。方法：选择2013年1月-2019年11月在笔者所在医院急诊治疗的冠心病室性心律失常患者98例，以给药时间为分界点，前49例为探究组采用胺碘酮治疗，后49例为比较组采用利多卡因治疗，对比两组临床指标、不良反应发生率等。结果：治疗后，相比于比较组，探究组的LVESD、LVEF、LVEDD同治疗前比较变化更明显，差异有统计学意义(P<0.05)。相比于比较组，探究组有效率更高，差异有统计学意义(P<0.05)。治疗前，两组临床指标差异无统计学意义(P>0.05);治疗后，相比于比较组，探究组的舒张压、收缩压、心率改善更明显，差异有统计学意义(P<0.05)。探究组不良反应发生率为6.12%，比较组为18.37%。和比较组相比，探究组不良反应发生率更低(P<0.05)。结论：急诊应用胺碘酮治疗冠心病室性心律失常的临床效果显著，值得推广。
【关键词】 胺碘酮 急诊 冠心病室性心律失常 治疗有效性
doi：10.14033/j.cnki.cfmr.2020.17.062 文献标识码 B 文章编号 1674-6805(2020)17-0-03
Clinical Study of Amiodarone in the Treatment of Ventricular Arrhythmia of Coronary Heart Disease/ZHAO Jinxiu. //Chinese and Foreign Medical Research， 2020， 18(17)： -147
[Abstract] Objective： To analyze the clinical effect of Amiodarone in the treatment of ventricular arrhythmia of coronary heart disease. Method： From January 2013 to November 2019， 98 patients with ventricular arrhythmia of coronary heart disease were treated in emergency department of our hospital. The first 49 patients (the study group) were treated with Amiodarone， and the last 49 patients (the comparison group) were treated with Lidocaine. The clinical indexes and adverse reactions of the two groups were compared. Result： After treatment， compared with the comparison group， the changes of LVESD， LVEF and LVEDD in the study group were more significant (P<0.05). Compared with the comparison group， the effect rate of the study group was higher， the difference was statistically significant (P<0.05). Before treatment， there were no significant differences in clinical indicators between the two groups (P>0.05). After treatment， compared with the comparison group， the diastolic blood pressure， systolic blood pressure and heart rate in the study group improved more significantly， and the differences were statistically significant (P<0.05). The incidence of adverse reactions was 6.12% in the study group and 18.37% in the comparison group. Compared with the comparison group， the incidence of adverse reactions was lower in the study group (P<0.05). Conclusion： The clinical effect of Amiodarone in the emergency treatment of ventricular arrhythmia of coronary heart disease is significant and worth popularizing.
[Key words] Amiodarone Emergency Ventricular arrhythmia of coronary heart disease Therapeutic effectiveness
First-author’s address： Guannan County People’s Hospital， Guannan 222500， China
冠心病為一类临床常见病、多发病。其有着进展速度快的特点，倘若患者没有在第一时间接受合理治疗，极有可能引起诸如心衰、心律失常、休克等症状，其在一定程度上威胁患者的生命安全。其中，室性心律失常较为常见，其危害性极高，另外也是导致病患猝死的高危因素。因此有必要使用有效方式控制患者病情。结合实际情况，本文全面探究急诊应用胺碘酮治疗冠心病室性心律失常的临床价值情况，现报告如下。, http://www.100md.com(赵锦秀)
【关键词】 胺碘酮 急诊 冠心病室性心律失常 治疗有效性
doi：10.14033/j.cnki.cfmr.2020.17.062 文献标识码 B 文章编号 1674-6805(2020)17-0-03
Clinical Study of Amiodarone in the Treatment of Ventricular Arrhythmia of Coronary Heart Disease/ZHAO Jinxiu. //Chinese and Foreign Medical Research， 2020， 18(17)： -147
[Abstract] Objective： To analyze the clinical effect of Amiodarone in the treatment of ventricular arrhythmia of coronary heart disease. Method： From January 2013 to November 2019， 98 patients with ventricular arrhythmia of coronary heart disease were treated in emergency department of our hospital. The first 49 patients (the study group) were treated with Amiodarone， and the last 49 patients (the comparison group) were treated with Lidocaine. The clinical indexes and adverse reactions of the two groups were compared. Result： After treatment， compared with the comparison group， the changes of LVESD， LVEF and LVEDD in the study group were more significant (P<0.05). Compared with the comparison group， the effect rate of the study group was higher， the difference was statistically significant (P<0.05). Before treatment， there were no significant differences in clinical indicators between the two groups (P>0.05). After treatment， compared with the comparison group， the diastolic blood pressure， systolic blood pressure and heart rate in the study group improved more significantly， and the differences were statistically significant (P<0.05). The incidence of adverse reactions was 6.12% in the study group and 18.37% in the comparison group. Compared with the comparison group， the incidence of adverse reactions was lower in the study group (P<0.05). Conclusion： The clinical effect of Amiodarone in the emergency treatment of ventricular arrhythmia of coronary heart disease is significant and worth popularizing.
[Key words] Amiodarone Emergency Ventricular arrhythmia of coronary heart disease Therapeutic effectiveness
First-author’s address： Guannan County People’s Hospital， Guannan 222500， China
冠心病為一类临床常见病、多发病。其有着进展速度快的特点，倘若患者没有在第一时间接受合理治疗，极有可能引起诸如心衰、心律失常、休克等症状，其在一定程度上威胁患者的生命安全。其中，室性心律失常较为常见，其危害性极高，另外也是导致病患猝死的高危因素。因此有必要使用有效方式控制患者病情。结合实际情况，本文全面探究急诊应用胺碘酮治疗冠心病室性心律失常的临床价值情况，现报告如下。, http://www.100md.com(赵锦秀)